Sinchai Tsao PhD is currently CEO at Voxel Healthcare. His expertise is in the intersection of machine learning and image analysis / computer vision to solve problems in healthcare.
Sinchai is focused on applying computational techniques to studying the neurological system at lifespan (from development to aging) including neurogenesis and degeneration, cortical folding, brain development and atrophy. Although we understand parts of these processes at a cellular and biochemical level, the exact biological mechanisms and their interconnected coordination that drive these processes at a systems level are widely unknown. This is especially true in the longer timescales and at the systems level. Medical imaging techniques, such as MRI, as well as advanced analysis of the resultant 3D or 4D large datasets have the potential to yield deep insights into these questions. These insights can be translated into designing better diagnostic tools for diagnosing pathologies arising from numerous conditions such as epilepsy, cancer, Alzheimer’s disease, etc. His current efforts are directed at translating tools and understanding in the lab into the clinic, including computational techniques that enable quantitative imaging.
Sinchai has more than 10 years of experience as a computational scientist working on multiple medical imaging problems such as: (1) machine learning-based classification of Malaria in pathology slides (2) using MRI metrics to investigate changes during Dementia and Aging (3) surface analysis of the developing human cerebral cortex (4) automated determination of skeletal bone age in children from hand x-rays.
Sinchai received his A.B. in International Relations and Sc.B. in Biophysics from Brown University and his M.S. in Electrical Engineering as well as M.S. & PhD in Biomedical Engineering from the Viterbi School of Engineering at University of Southern California. He is a graduate of the CIBORG Laboratory at USC/Children’s Hospital Los Angeles, where his advisor was Natasha Lepore, PhD. He was also part of Manbir Singh, PhD‘s Biomedical Imaging Lab before his passing in Dec, 2011. During his time in Los Angeles, he also served as Director of Engineering Curriculum for Iridescent Learning – a science education 501c3 non-profit. Sinchai then moved to Seattle where he did his postdoctoral training at University of Washington’s Biomedical Image Computing Group in the Division of Neonatology, Department of Pediatrics. After his postdoc, he was a scientific software engineering consultant for Malaria Diagnostics as well as Ultrasound Diagnostics at Intellectual Ventures Labs in Bellevue, WA.